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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

Meanwhile, exports are expected to continue falling due to the combination of weak global demand and higher prices, as well as China’s decision to effectively re-peg the renminbi to the strengthening dollar.
“目前市场上有大量尖端,环保的人造皮草,我相信你会同意现在没有任何借口来杀死动物以获取皮草了。”

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

Only two people know the Oscars winners list and supervise the counting procedures - PwC tax adviser Martha Ruiz and Brian Cullinan an accountant.
007系列电影主题曲第一名:雪莉·巴赛--《金手指》

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

The country has rolled out measures to promote new-energy vehicles, including tax exemptions, subsidies for car purchases and a requirement for government departments to buy more new-energy cars.

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

If there are nine or 10 best picture nominees, it could grab a spot. Jordan Peele's screenplay looks certain to be recognized.

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
From the themed collection: 前7个月房地产开发投资好于预期
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

Enrollment: 503
通常在垃圾桶里东西是没有价值的,不需要任何检查,但Qube试图用“世界上第一个智能垃圾桶”来改变这一现状。Qube声称可以帮助你监控你的垃圾,帮助你利用创新技术回收垃圾。
Age: 39
After months have passed without a culprit in her daughter's murder case, Mildred Hayesmakes a bold move, painting three signs leading into her town with a controversial message directed at William Willoughby, the town's revered chief of police. When his second-in-command Officer Dixon, an immature mother's boy with a penchant for violence, gets involved, the battle between Mildred and Ebbing's law enforcement is only exacerbated.

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

国家统计局在发布最新数据的同时进行了解读,它将PPI连续上涨部分归因于煤炭开采和洗选业价格同比上涨15.4%,这一涨幅比上月扩大11.3个百分点。
它还体现在萝塞拉·亚尔迪尼(Rossella Jardini)为莫斯奇诺(Moschino)设计的2009年春夏系列的蝴蝶结和宽松裙子上以及以玛丽·匡特(Mary Quant)为灵感的2013年春季系列中。
PwC has counted votes and provides winner envelopes for the Oscars and has done so for more than 80 years. This is the first time in Oscar history that the wrong envelope had been opened while an award was being announced.
The 2017 FT executive education rankings include the best 85 customised programmes and the best 75 open-enrolment programmes worldwide. The rankings are based principally on measures of participants’ and clients’ satisfaction, as well as the schools’ growth in revenues, their international reach and faculty diversity.

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

智能垃圾桶

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
From the themed collection: 不动产登记平台已实现全国联网
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

优秀的老板们懂得授权的艺术。我的一位评论家说要沿着线走“他们已经从目前的工作里面抽身”,意味着他们不干涉每一天和每一分的工作流程和程序。本质上,学着去授权给员工去代替微化管理是对员工的一种信任。

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
From the themed collection: 进口家具市场混乱 阻碍消费购买
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

《盗墓笔记》
check原是检查的意思,后来有这么一帮人喜欢突然阻止你,检查你的暂住证,所以就有了突然阻止的意思。

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

May you have the best New Year ever.愿你度过最美好的新年!
我们进行一个比较,佳士得和苏富比的这两次18世纪前绘画大师作品拍卖会共拍得2910万英镑,比五年前(2011年12月)类似拍卖会拍得的4420万英镑少了34%。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

在经过了漫长的海选和五天紧张的半决赛之后,11位候选选手中其中一位成为了第八季英国达人秀2014年的冠军。
For the fifth year in a row the city-state's Changi Airport has been named "world's best airport" at the annual Skytrax World Airport Awards.

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

如今,蓬勃发展的互联网经济在支撑我国信息技术(IT)行业财富增长方面正发挥着越来越重要的作用。
单词inspection 联想记忆:
受到密切关注的财新(Caixin)采购经理人指数(PMI)系列调查显示,该指数在四个月来首次显示扩张趋势。这一结果表明,上个月中国经济活动出现了增长。
2. 宾夕法尼亚大学沃顿商学院

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

反对:纽约时和洛杉矶影评人协会都对该片无感。

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

尤塞恩?博尔特是搜索次数最多的非英国籍奥运会选手。
J.P. Morgan slides to fourth place as its total composite score slipped behind Agricultural Bank of China. Say goodbye to the two Europe-based companies in Top 10 last year, Royal Dutch Shell (No.11) and HSBC Holdings (No.14).

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

排行榜的最新单曲有Shawn的《There's Nothing Holdin' Me Back》,击败DJ Khaled 的《Wild Thoughts ft. Rihanna》和Ed Sheeran的热播曲目《shape of you》,以及放了播破纪录Addy Yankee & Luis Fonsi的《Despacito》。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

Here are five things consumers and investors can count on (probably) in 2015:

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

达洛伊西奥也尽力维持着生活原本的样子。他的女友还是之前的那个女友。而且尽管他不再去学校了──坐在教室里就没空监管Summly的研发──他还是照常去找老师拿作业。他十分庆幸他的朋友不了解他企业家的那一面。而当我采访他的时候,他正准备和一群高中死党去希腊玩上一周。
蒋依依说,2013年人民币兑美元汇率上涨近3%,使北京成为了一个更加昂贵的旅游目的地。
同行评审指由一个或多个与论文作者业务能力相当的人进行评估,这有助于对研究进行验证。
Britney, YOU drive me crazy for appearing on Loose Women smacking gum like it's 1998 as the panel interrogate you.

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

《寻梦环游记》
《生活大爆炸》中绝不缺少天才。不只是因为这部剧向观众展示了很多绝顶聪明的科学家,同时,演员玛伊姆·比亚利克还拥有神经学博士学位。因此,演员们想要在剧中展示他们的聪明才智,并将整部剧做到精益求精,这也不足为奇。剧中谢尔顿和莱纳德的公寓里有一块很大的白板,这对铁哥们几乎在处理任何事时都会用到它,从完成从学校带回来的工作,到决定是否等到看完最新一部《蜘蛛侠》再吃饭,都离不开这块白板。
['m?dist]
Finance is one of top school Edhec’s core strengths, both in terms of teaching and research. The school in 2001 established the Edhec-Risk Institute to produce and distribute research on areas such as asset and risk management.
Dachis says: The end of year iPhone 5 and iPad Mini releases overcame early controversies in overseas manufacturing and any lingering effects from the death of Steve Jobs to make Apple the biggest mover of the year.

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

A woman's portrait has not been printed on U.S. paper money since 1896, when Martha Washington, the wife of the first U.S. president, was shown on a one dollar silver certificate.
在NBA,很少人能防得住罗斯。那么,你可以想象,在罗斯的高中年代,有着和现在一样的NBA身板,要防住他更是天方夜谭。

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

摩根士丹利的分析师乔纳斯认为,Model X的销量将会更加可观,但不是由于它的燃油经济性,而是它升级后的信息娱乐系统,以及独特的“鹰翼”式后车门。他还表示,如果Model X没有赢得所有的年度车型大奖,他会非常失望。他并不是唯一一个这样想的人。埃隆o穆斯克和其他很多祈祷特斯拉继续保持当前势头的人当然也会这样想。(财富中文网)

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

他说,本周早些时候他和美国国务卿克里的会谈显示,美国准备朝“解决只有通过共同努力方能解决的问题”的方向发展。

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

理查三世是金雀花王朝的最后一位国君,都铎王朝的继任者将其塑造成了不惜一切代价追求权力的无恶不作的暴君,还称他谋杀了他的两个侄子-也就是“塔中王子”-来保住王位。
Inside larger technology companies, female employees will be hoping for signs of change in pay and promotions — but will also be on guard, as a men’s rights backlash brews in some corners of Silicon Valley.
在经过一段漫长而艰辛的竞选活动后,美国当地时间11月6日,美国总统奥巴马战胜了共和党候选人罗姆尼,胜出2012美国总统大选成功连任,将迎来执政白宫的第二个任期。
Jobs for photographers grew by about 22 percent in Q3. The report’s authors attribute the increase to employers “finally understanding the importance of high-quality pictures on their landing pages.” The desire to expand and improve websites through employing trained, creative professionals was something of a recurring theme throughout this list.

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

She’s No. 1: Chancellor Merkel has made the list eight times out of the past ten years — seven times as No. 1.
最坏习惯奖
净利差——即贷款和存款的利率之差——在降低,因为中国撤销了对存款利率的剩余管制。2015年,中国银行业平均利差下降约46个基点,至2.54%。
别提什么至少提前两周通知公司,精心安排一次离职面谈,在卷铺盖走人前费尽心机跟人搞好关系了。有些人在离职时太过匆忙,根本顾不上这些套路。

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

分析师和评论员们对石油市场的解读着重于供应端,以及沙特或其他地方的产量和出口量。供给很重要,但成本更重要。
[.k?lkju'lein]

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

A thin line separates confidence and delusion, and Kobe Bryant is straddling it. It's the only conclusion one could reach after judging the Los Angeles Lakers star's comments Tuesday after he tied the worst shooting performance of his career in any game in which he attempted at least five shots.
一定要展现自己过人的智慧,努力地表现出心神不定的样子。把那些社交技巧抛到脑后吧!
With very best wishes for your happiness in the New Year.
你永远都不能把一只狼变成宠物狗。
jail

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

Let’s never spend our New Year apart.让我们永不独享新年。
春运是中国在农历春节前后发生的一种大规模的高交通运输压力的现象,尤其是火车运输方面的压力。
昨日发布的央行数据显示,中国外汇储备上月出现有记录以来第三大单月降幅。这重燃了人们对于中国遭遇资本外流的担忧,此前中国外汇储备似乎企稳。

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

11. Am I dwelling on the past? It is very tempting and almost involuntary to look back on the past and obsess over something we regret or something we miss. Learn to let go and only focus on what’s happening right now, and on the choices you will make today.
4. 2012年搞笑诺贝尔奖之神经科学奖

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
From the themed collection: 北京“官批”28日19时正式闭市
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

单词exceed 联想记忆:
普兰特?莫兰:甜食福利惹人馋
单词receptive 联想记忆:

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

护符距今已有3200年的历史,上面还刻有“图特摩斯三世”法老的名字。他于公元前1504至公元前1450年在位统治。
3. The root cause of eczema has finally been identified. Scientists have tracked down a series of proteins and molecular pathways that lead to this insufferable skin problem, revealing that the protein filaggrin isn't the sole culprit we thought it was.
15. 有趣的巧合。环球影业是题材最具多样性的制片公司之一,它发行了《生活残骸》,也发行了《冲出康普顿》,还有《泰迪熊2》(Ted 2)。环球影业的女导演也是最多的,12月初,它占据了今年24%的市场份额。

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
From the themed collection: 智能家居或成BAT下一个竞逐点
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

From the themed collection: 盘点上过央视的木门品牌
Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

The Big Tech backlash will spread to technology industry employees in 2018, as many question whether the work they do really is saving the world.

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

尽管随着2014年末几项官司尘埃落定,手机专利战争似乎已经降温,但新年伊始,苹果与爱立信就又在无线通讯的专利费率上爆发冲突。黑莓过去就是一家热爱诉讼的公司:他们甚至因为名人瑞安o西克雷斯特设计的手机键盘而起诉他。但近些日子以来,公司更多地把工作重心放在了让智能手机消费者相信他们的技术依旧很棒,或至少很有意义上。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

Hello, I'm Severn Suzuki speaking for E.C.O. - The Environmental Children's Organisation. 大家好,我是Severn Suzuki,我代表儿童环境组织来此演讲。
提到MeToo行动,麦高恩说:“他们都是混蛋,不是冠军,一群失败者,我不喜欢他们。”

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

Epic Games游戏工作室对包括迦勒·罗杰斯在内的两个人进行了法律诉讼,因为他们使用作弊软件来玩《堡垒之夜》这个游戏。
Cnzz.com的报告说,目前中国3.38亿网民中有将近三分之二都是网络游戏玩家。报告说,中国网络游戏行业目前占据了互联网经济总规模的半数以上,在未来还将以每年20%的速度增长。
The studio says it has taken the step because the boy declined to remove a YouTube video he published which promoted how to use the software.
Facebook CEO Mark Zuckerberg

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

库克已在先前以白人男性为主的苹果管理团队里增加了三位女性,还改变了苹果的董事会章程,承诺任命董事时会从少数群体中挑选候选对象。
去年12月初,中国有关部门宣布将于今年1月1日起实施股市熔断机制,以限制股市再出现去年6月夏季大抛售时的波动。当股票、期权和期货下跌逾5%,将触发熔断机制,交易将暂停15分钟。今天是熔断机制启用的第一天,下午刚一开盘,于当地时间下午1:14分,A股市场就突破了第一道阈值,触发停盘15分钟。当交易恢复后,5分钟内大盘继续下跌了2%,二度触发熔断机制。

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
From the themed collection: 地产股短线反弹 明年压力不小
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

ap+prove=test测试,证明→证明可行→赞成;承认+al→赞成
In Belgium's case, the reasons are more readily apparent. A nation sewn largely from a patchwork of three peoples, the Flemish, Walloons, and Germans, its football team nevertheless features several stars of African descent. Currently, Belgians of Moroccan descent -- including midfielder Marouane Fellaini and winger Nacer Chadli -- make up the biggest non-European group; for many Moroccans, French is a second language. Like France with its North African and Caribbean contingents and Germany with its Turks, Belgium's national team has benefited from multiple populations: one from Western Europe, one from Africa, and one from Eastern Europe.

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
From the themed collection: 刷脸入住智慧酒店 满屋黑科技
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

6. 谷歌搜索广告关键词规划工具

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

Renters
However, its alumni are the most mobile internationally, with 85 per cent of the class of 2014 having worked abroad.
理查三世是金雀花王朝的最后一位国君,都铎王朝的继任者将其塑造成了不惜一切代价追求权力的无恶不作的暴君,还称他谋杀了他的两个侄子-也就是“塔中王子”-来保住王位。
当支持者在周一早些时候涌向总督大楼,一人高喊,"今天,新的波多黎各开始了!" 随着其他人的欢呼,包括那些拿着美国国旗的群众。

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

即使我们把吉布森视作租赁合同并且他将在夏天离开,雷霆对这笔交易依然感觉良好。
Anyway, it's nice to see that LeBron has filled into his monster physique nicely in the past nine years.

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

这块白板经常被写满公式。但你是否曾好奇过这些公式都有什么含义?我们也许没有机会知道它们代表什么,但它们的确都是真实准确的公式。这一点相当给力。
添加一些个性元素。把自己家人的照片或东西放在桌子上可以提醒你为什么你要努力工作。
3.3 进一步释放国内需求潜力

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

vigil醒着的+ance表名词,“性质,状况”→警惕
三大能源机构近期表示,今年石油输出国组织(Organization of the Petroleum Exporting Countries, 简称:欧佩克)以外国家的原油产量将增加,其中大部分来自美国的页岩油。除此之外,由于伊朗、伊拉克和利比亚可能会增产,中东地区的原油产量也许会增加数百万桶。所有这些势必会令油价承压。
国内航空统计公司飞常准发布的最新报告显示,我国主要机场的准点率仍然远未让人满意。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

值得注意的是,本年度传播假消息之首的网站域名当属“abcnews.com.co.” 在十一月的一次Verge的采访中,伊利诺伊州大学信息科学学院的Nicole A. Cooke教授引用了一个假新闻网站上的消息,这个假新闻网站使用的是危险和普遍的策略,即域名和真网站看上去只有微小的区别。他们让消息源从第一眼看上去具备真实性。管理abcnews.com.co的人告诉华盛顿邮报,他相信他的网站在特朗普大选期间充当了一个重要的因素。
Perhaps it will not catch on in the cut-throat world of Wall Street. Some may see an extended absence as an admission that their jobs are expendable, and that colleagues can survive — and perhaps thrive — without them.

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
From the themed collection: 山西省经济发展信心不断增强
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

championship
SIZE: 3,073 square feet
戴假牙的角色

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

New Year’s greetings and best wishes!致新年贺忱与最美好的祝福!
One of the more unique games announced at Gamescom was Silent Hills, the latest sequel in Konami’s bestselling horror franchise (which has also spawned two films). The world of gaming and movies combine in this new game, which is being developed by Metal Gear Solid V: The Phantom Pain creator Hideo Kojima and Pacific Rim director Guillermo del Toro. The game will star The Walking Dead’s Norman Reedus.

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

莎拉奥康纳(Sarah O'Connor)是就业记者
Christopher Nolan's World War II feature is probably just about the front runner for best film.
尼古拉斯·凯奇(Nicolas Cage)向来不随大流,他曾向媒体透露,因为居住权问题,他因影片《离开拉斯维加斯》(Leaving Las Vegas)所获得的小金人“正在某辆卡车上穿越路易斯安那州”。显然,如果政府要对你查户口,问问你的小金人在何处就可以了。

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

就业市场面临着挑战。约有500万美国人失业已有六个月之久,技能退化令他们未来更难找到工作的风险也加大。此外,收入增长放缓引发的担忧可能会限制企业招聘。据咨询公司CEB今年10月进行的一项调查显示,约有36%的美国高管预计其公司的职员人数会减少;相比之下,今年夏天这一比例为29%。[qh]

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

这些专家都不是轻量级的。杰出的历史学家玛格丽特?麦克米伦(Margaret MacMillan)在2013年12月的一篇为布鲁金斯学会(Brookings)撰写的文章中说:“像1914年的世界一样,我们正在经历国际权力结构的转换,新兴大国正在挑战老牌大国。”她补充说,“如今,同样的一幕正发生在美国与中国,以及中国与日本之间”,同时她还表示,“中国与它另外两个邻国——越南和马来西亚——也有爆发冲突的可能性。”
2016年观影人数达到13.7亿人次,同比增长近8.9%。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

In the big closing session of the World Economic Forum in Davos, they recognised risks existed and badly run emerging markets might be vulnerable to shocks, but concluded that the outlook was brighter than it has been for many years.
[ai'dentiti]

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

2018年,反对科技巨擘(Big Tech)的声音将扩散到科技行业雇员群体,很多人质疑他们所做的工作是否真的在拯救世界。
['?n'steibl]

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

That's a fraction of their earning power -- Hillary and Bill Clinton banked $10.6 million mostly from speaking fees and royalties in 2015, while Trump said he made almost $560 million.
如果有什么电影能够至少在两个小时里,为美国生活中深刻的种族、代际与阶层鸿沟架起桥梁,那可能就是这部古老的《洛基》(Rocky)系列的复活影片。西尔维斯特·史泰龙(Sylvester Stallone)拖着脚步,饰演这个聪明的老教练角色,给出了他演艺生涯中或许是最松弛、最温暖的表演。迈克尔·B·乔丹饰演洛基的被保护人阿多尼斯·约翰逊(Adonis Johnson),他也是洛基一度的竞争对手和早已丧失的朋友阿波罗·奎迪(Apollo Creed)的私生子,他成了我们这个时代重要的影星。至于库格勒,这是他执导的第二部唱片,证明他是一个真正的斗士。

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
From the themed collection: 快讯:沪指跌破2700点
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

A mother has written a letter in defence of her 14-year-old son who is facing a lawsuit over video game cheats in the US.

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

捷克模特皮德拉·尼姆科娃选择了一件白色连衣裙,这件裙子的特色就是深V领口以及长及大腿的裙摆开叉。这位极有魅力的金发女郎极力突出自己轻盈的美腿,确保自己走上红毯的时候可以吸引所有人的目光。
"The Hunger Games" star ranks first on the 2012 edition of AskMen.com's "Top 99 Most Desirable Women" list. The poll, which collected more than 2.4 million votes, asked the website's readers to choose their favorite female celebrities based on their looks, personality, talent and other desirable characteristics.
“四个全面”战略布局:全面建成小康社会是我们的战略目标,全面深化改革、全面依法治国、全面从严治党是三大战略举措
A lack of capital and experience is the biggest obstacle for college entrepreneurs, the report suggested, stating that 40 percent of such young entrepreneurs rely on external capital such as loans from banks, investment organizations, schools and the government.

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

《哈利·波特》粉们,福利来啦!该片是《哈利·波特》前传,讲述了纽特·斯卡曼德在老纽约的冒险经历。该片根据《哈利·波特》中霍格沃兹学院的同名教科书改编而成。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

约40%的创业者的大部分收入都来自自己的公司,平均薪资约为19.4万美元,而非创业者的平均薪酬为17.1万美元。亚洲和大洋洲的创业者看起来是最成功的。他们中近一半人(48%)的大部分收入都来自自己的公司,而且薪资最高(平均为25.1万美元),稍高于中东的创业者(24.4万美元)。
“理查三世研究小组”的成员菲利帕?朗丽说,她希望能重塑理查三世的形象,都铎王朝的继任者塑造出来的片面形象将不复存在。她负责协调研究工作以及筹款。
The highest average monthly salary for 2016 graduates is 5693 Yuan in IT/Internet/telecommunications/electronics industries; second is financial industry and culture/sports/entertainment/media industries with average salaries level of 4685 Yuan and 4552 Yuan respectively; monthly salaries in agricultural/forest/grassland farming/fishing, and services/ educational sports/industrial arts are relatively low among signed graduates, respectively are 3500 Yuan, 3873 Yuan and 3900 Yuan.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

公司:建筑公司Project Frog
《速度与激情6》帮助其另外两位男演员在我们榜单中获得较高的排名:范·迪塞尔(Vin Diesel)和已故的保罗·沃克(Paul Walker)。迪塞尔以8.87亿美元位居我们榜单第四。《速度与激情6》在全球斩获7.89亿美元的票房。仅仅几个月之前,他出演的《星际传奇3》(Riddick)在各大影院上映,仅收入9,800万美元票房,不过,这也足以使迪塞尔的排名领先于他的搭档沃克。

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

“…called the interviewer by the wrong name.”
10. Deepika Padukone - $10 million

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
From the themed collection: 线上还是线下家居品牌站队难
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

虽然与其他四部电视剧相比,《大唐荣耀》的评分并不算低,但是仍然有许多观众给出了差评。

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

在这个风云变幻的世界,詹姆斯·邦德俘获了不少铁杆粉丝,是至今为数不多的仍在续拍的电影之一。在人们的意识里,无论发生什么事情,新的007电影依然会拍下去。
This compared to a decade ago when there were six Asian cities, 10 European cities and four US cities in the top 20 of the list that calculates living costs in 131 cities in 93 countries and is used by companies for costings when relocating staff.
这支队伍需要更多的天赋,他们需要大修。对魔术而言,最能吸引天赋到来的方式一直以来都是选秀。

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

You're the best present I ever received.你是我所收到的最好的礼物。
与工商管理硕士(MBA)不同,管理学硕士项目针对的是尚未进入职场或者初入职场的人士。
2. Google Docs
2015年英国《金融时报》全球高管工商管理硕士课程(Global Executive MBA,简称全球EMBA)排行榜由于两个原因而引人注目。不仅因为这是英国《金融时报》发布的第100个商学院排行榜,也是因为今年首次有一个主办方包含一所中国内地商学院的项目拔得头筹。

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

Among French schools, Toulouse Business School made the best progress, up 14 places, after featuring in the Executive MBA ranking for the first time.
8. Trang Islands, Thailand-The islands of Trang, a sleepy province in southeast Thailand, have remained under the radar. Wooden longtail boats can be rented to travel between the islands—and to see the endangered dugongs.

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
From the themed collection: “一房二卖”引发了5起连环官司
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

The report provided in-depth observations on 28 Chinese business and administrative capitals - excluding Beijing and Shanghai - using several indicators.
“常见物乱更名奖”,每年都是我的心头好。几年前,Speedo曾将泳帽改称为 “头发管理系统”(hair management system)。去年,Falke更绝,将一款袜子称作“生活问题解决方案”(Life Performance Solutions)。
3. Kraft. Brand love: -10% / Rank: 11

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
156 items - Showing page 1 of 3

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每个企业家平均会使用十几个云软件和应用。Zapier可以把你的网络生活联系起来,帮助你构建新的功能。Zapier最好的一点就是,你甚至不需要懂API就可以使用它。
Elspeth Cheung, head of BrandZ valuation at Millward Brown, says: “The top 10 used to be dominated by consumer goods. This year, it’s technology.”

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